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ATAXIA TELANGIECTASIA MUTATED PROTEINS
Descriptors Found:
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DeCS
Descriptor
English
:
Ataxia Telangiectasia Mutated Proteins
Descriptor
Spanish
:
Proteínas de la Ataxia Telangiectasia Mutada
Descriptor
Portuguese
:
Proteínas Mutadas de Ataxia Telangiectasia
Synonyms
English
:
A-T Protein
AT Mutated Protein
ATM Protein
A T Protein
Mutated Protein, AT
Protein, A-T
Protein, AT Mutated
Tree Number:
D08.811.913.696.620.682.700.097
D12.776.157.687.125
D12.776.660.720.125
Definition
English
:
A group of
PROTEIN-SERINE-THREONINE KINASES
which activate critical signaling cascades in double strand breaks,
APOPTOSIS
, and GENOTOXIC STRESS such as ionizing ultraviolet A light, thereby acting as a
DNA damage
sensor. These
proteins
play a role in a wide range of signaling mechanisms in
cell cycle
control.
History Note
English
:
2014
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
55299
Unique Identifier:
D064007
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS